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Clinical Research

Surgeons for Little Lives continues to impact pediatric surgical care through our latest clinical research.

Clinical outcomes of intussusception: The experience in Johannesburg, South Africa

A previous study on intussusception from our institution demonstrated a pneumatic reduction (PR) rate of 33%, with a mortality rate of 9.1%. Numerous protocol changes were implemented, and as part of a national prospective observational study, a subsequent cohort of patients was compared with the initial series.

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May 14, 2025
A historical overview of paediatric surgery at Wits University: From embryo to adult

History provides wonderful insights into how society develops, providing innumerable lessons that can be used as individuals and institutions move into the future. The history of medicine provides particular value, yet it is so often overlooked by the present, society taking for granted what has often been a tremendous struggle to achieve. This overview of the history of paediatric surgery at the University of the Witwatersrand provides amazing insights into what has been achieved in a period spanning three centuries.

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May 14, 2025
The versatility of median sternotomy in general paediatric surgery

While common in cardiac surgery, median sternotomy (MS) is rarely required in general paediatric surgery. In the era of advancing endoscopic techniques, sternotomy is perceived as an extremely invasive incision, associated with prolonged postoperative recovery and significant morbidity.

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May 14, 2025
Telephonic followโ€up after day case pediatric surgery in an upper middle income country: A pilot study

One third of South African children live in households with no employed adult. Telemedicine may save patients and the strained public health sector significant resources. We aimed to determine the safety and benefits of telephonic postโ€operative followโ€up of patients who presented for day case surgery at CHBAH from 1 Januaryโ€“31 March 2023.

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May 14, 2025
A 7-year retrospective review of renal trauma in paediatric patients in Johannesburg

South African data on paediatric patients with renal trauma that are usually managed conservatively is scarce. This study aimed to review a 7-year experience of paediatric renal trauma and management.

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May 14, 2025
A perspective on paediatric surgical training: opportunities and challenges

Globally, the training of paediatric surgeons is facing numerous challenges. Exposure to rare and complex index pathology is vital in the training of competent paediatric surgeons, but it is this rarity and complexity that creates a fundamental challenge to training programmes the world over.

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May 14, 2025
A retrospective study analysing mortality and outcomes in the paediatric burns intensive care unit at the Chris Hani Baragwanath Academic Hospital, Johannesburg

Data on mortalities related to paediatric burns in South Africa are scarce and outcomes in transferred and direct admissions into paediatric intensive care units have not been compared.

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May 14, 2025
Neonatal surgical outcomes: a prospective observational study at a Tertiary Academic Hospital in Johannesburg, South Africa

The neonatal period is the most vulnerable period for a child. There is a paucity of data on the burden of neonatal surgical disease in our setting. The aim of this study was to describe the frequency with which index neonatal surgical conditions are seen within our setting and to document the 30-day outcome of these patients.

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May 14, 2025
Pediatric minimally invasive surgery in Africa: limitations and current situation

The second largest and most populous continent, with an exploding pediatric population, Africa has an overwhelming burden on its very limited pediatric surgical services. In an international environment of progressively advancing endoscopic and robotic surgical techniques, the authors focus on the current role of endoscopic surgery on the continent and explore the potential reasons for its delayed acceptance and implementation.

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May 14, 2025
Factors determining clinical outcomes in intussusception in the developing world: Experience from Johannesburg, South Africa

Rates of open reduction of intussusception were noted to be unacceptably high during an institutional internal audit.

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May 14, 2025
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